My 4-year-old
has been diagnosed as asthmatic by the pediatrician. What can we expect?
Asthma is extremely
common; fortunately, many children grow out of their asthma in adolescence.
Asthma is an inflammatory condition of the lungs and airways, most marked by
bronchospasm.
Asthmatics are
especially sensitive to such factors as dust, mold, animal dander from pets,
cold, exercise, and sometimes aspirin. The airways become thickened and swollen
(the inflammation) and constrict (the spasm). This narrowing is most marked
in expiration, so the wheeze is usually in breathing out, which the child feels
as tightness in the chest.
It is important
to be sure there are no other conditions presenting themselves as asthma. Usually
a child shows asthmatic symptoms when experiencing an upper respiratory infection.
A family doctor
often treats mild asthma, but more severe forms are probably better treated
by physicians specializing in respiratory problems.
The most common
treatment is with a bronchodilator, which may be used before exercise or when
symptomatic. The inhaler is the most common route of administration, though
tablets, capsules, and injections may be required. The medicine used is an agent
that stimulates B2 receptors and relaxes the smooth muscles of the bronchi.
Some anti-inflammatory
agents may be required if the bronchodilators are inefficient. Again, inhalation
of a corticosteroid-like medication is usually effective. A recent study showed
a 50 percent reduction in hospitalizations in people using prophylactic steroids.
For children, a new group of medicines called "mastcell stabilizers"
and "leukotriene modifiers" is showing promise.
Removing triggers
from the environment can be very important: a dust-free environment, a pet-free
house, damp dusting, hardwood floors, synthetic pillows and bedding. You should
work out an asthma attack plan with your doctor. Understand what the medications
you have been given are for and how they work. Be regular in giving the medication.
Keep a list of everything you are using to show a doctor who may be unfamiliar
with your problems.
Hopefully, with
the growth of the airway, your little one will find that he or she is less significantly
constricted and that the asthma becomes a problem of the past. Until then, follow
your doctor's advice carefully.
I am trying
to lower my cholesterol. I'm a vegan, I exercise, I have a normal weight, and
I don't smoke or drink. Though my cholesterol readings have improved, the doctor
is still not satisfied. I'm especially concerned because my father died at age
51 of a heart attack, even though he was apparently quite healthy until then.
My doctor wants to put me on Zocor. What do you think?
Well, you seem
to be doing all the things a person can do to live a healthy life. You definitely
have taken care of the lifestyle component of health. One of the most difficult
things for Adventists to realize is that we are broken; we can't work out all
of our own health problems and live forever any more than we can work out our
own salvation. That doesn't mean giving up. You are definitely better off than
you would be if you lived a reckless lifestyle.
I would recommend you take the Zocor your doctor has prescribed. If your lifestyle
changes had worked sufficiently, you might not have needed it. However, it seems
that at least part of your problem is very likely genetic.
Zocor belongs
to the statin group of medications used principally to lower cholesterol levels
(by inhibiting the production of cholesterol). A very strong base of evidence
shows increased survival among patients using these statin medications. No medication
is without potential side effects, and you need to discuss these with your doctor.
However, some other interesting side effects have been reported about the statin
medications.
In the November
11, 2000, Lancet, a large study on about 60,000 people found those on statin
had a substantial reduction in the incidence of dementia and loss of memory.
In fact, the group had better abstract thinking abilities than those not on
statin. This effect was seen with the statin group of cholesterol-lowering medications,
but not with other kinds of cholesterol-lowering medications. This lowering
of risk amounted to 70 percent for Alzhei-mer's disease. This study was not
a randomized study, so we await further evidence. If true, it is a nice additive
effect to an already-proven benefit in regard to heart disease protection.
One of the statins-Baycol
(cerivastatin)-was withdrawn from the market because of muscle breakdown and
resultant kidney problems, but the other statins have not been shown to have
side effects as significant. If the doctor feels you should take the medication,
a vast body of compelling evidence exists to support its use.
I am concerned
about the smallpox vaccination. How safe would it be? Is there any way to treat
smallpox that would avoid vaccination if there were to be a terrorist attack
using this germ?
Here we are, 25
years after we thought smallpox had become extinct, worrying about it again.
The problem lies in the fact that stocks of the virus called "variola major"
were held in "safe" keeping in laboratories in the U.S.A. and Russia.
Concern centers on whether supplies of the virus have fallen into the hands
of terrorists. How real such a scenario is we don't pretend to know. Nevertheless,
a single case of smallpox would be far more dangerous and liable to spread than
a case of anthrax.
The logistics
of spreading the disease seem enormous, but willing "suicide" carriers
could inoculate others they contacted. The disease causes severe morbidity,
which might limit the ability of infected terrorists to interact with others,
but epidemics were the norm in the days before immunization, and so epidemics
could be expected in today's populations, which are currently not immune.
Smallpox has a
30 percent morbidity rate. The U.S.A. population is largely not immune, because
the vaccination program stopped in 1971 for the general public and in 1990 for
military personnel. There are 15.4 million doses of the old vaccine in stock.
Vaccine production had stopped, so the call for vaccines for the entire population
by 2003 likely will be of a virus cultured in human cell lines. The old method
was to take lymph from cattle inoculated with the vaccinia virus and scratch
some of it into the skin. The newer vaccines will not have had time for large-scale
studies.
Smallpox vaccination
is hazardous in those who are immuno-compromised, such as HIV-positive persons.
People with skin disease such as eczema are also at increased risk of wide dissemination
of the vaccine-produced pustules through the skin.
Rare but devastating
is smallpox encephalopathy, which usually kills the unfortunate victim.
Though these complications
are nasty, they are insignificant compared to the effects of a smallpox epidemic.
For now, it's not wise to immunize the whole population, but should there be
a terrorist attack, the best defense would be mass vaccination.
No dependable
treatment exists. Those of us immunized years ago are probably quite susceptible
and would need reimmunization. The U.S. government's expenditure of $428 million
to produce a vaccine indicates a real concern on its part regarding the degree
of risk. For now, all we can do is be alert and not get too anxious about matters
we hope will not happen and over which we have no control.
_____________________________ Allan R. Handysides, M.B., Ch.B., F.R.C.P.(c), F.R.C.S.(c), is director of
the General Conference of Seventh-day Adventists Health Ministries Department;
Peter N. Landless, M.B., B.Ch., M.Med., F.C.P. (SA), is I.C.P.A. executive director
and associate director of the General Conference Health Ministries Department.